Two astronauts (Dennis Quaid, Vantage Point and Ben Foster, X-Men 3) awaken in a hyper-sleep chamber aboard a seemingly abandoned spacecraft. They have no memory of who they are or what their mission is but one thing they do realise very quickly is that they are not alone. As they uncover the spacecraft's deadly secrets, the astronauts are forced into a desperate fight for their lives as it becomes clear that their survival is more important that they could have ever imagined.