Generations from now, civilization has been obliterated and both humans and animals have devolved back to the Stone Age. Now, a tribe of post-apocalyptic warriors lead by Sean Bean (Black Death, The Lord of the Rings) must fight to survive in a barren world of jungles, deserts and primeval wetlands that was once New York City. After their last outpost is attacked by genetically mutating beasts, they must set out to find other humans in a desperate attempt to defeat the disease that decimated the world, save the human race, and restart civilization.